Immune Repertoire Analysis
with Vidjil

Rennes (France), 22-23 May 2024

V(D)J recombinations in lymphocytes are essential for immunological diversity. They are also useful markers of pathologies, and in leukemia, are used to quantify the minimal residual disease during patient follow-up. High-throughput sequencing (NGS/HTS) now enables the deep sequencing of lymphoid populations. With dedicated Rep-Seq bioinformatics methods and software, clinicians and researchers can now qualify and sometimes quantify the heterogeneity of these lymphoid populations.

This sixth workshop is intended for users and developers of Vidjil, to share experience, protocols and results, to raise questions and decide development priorities, and possibly to set up new collaborations between biologists and bioinformaticians. The workshop will include invited talks, hematology, immunology and bioinformatics talks from the users and developers of Vidjil, and practical hands-on sessions on participant data. The Vidjil Workshop usually takes place every 18 months. The previous workshops (2016, 2017, 2019, 2020, 2022) gathered at each edition between 30 and 40 scientists from 5 to 7 countries.


Preliminary Program

A more detailed program will be available early May 2024. The workshop includes invited talks, hematology and bioinformatics talks from the users and developers of Vidjil, and practical hands-on sessions on participant data. We expect that one participant from each group will do a short presentation of his research or clinical work, and, if applicable, of the results obtained with Vidjil or with other software.

For the practical sessions, the participants are invited to bring a laptop and some of their NGS data (fasta / fastq / fastq.gz files). The data can also be uploaded before the workshop into user accounts on app.vidjil.org before the workshop. We also provide public test data for the people who do not currently have their own NGS Rep-Seq data.

Wednesday 22 May

9:00 – 9:45 Registration, coffee
9:45 – 10:00 Introduction
10:00 – 12:30 Keynote talk (TBA)
Talks: Algorithmics and bioinformatics
  • Florian Thonier, How to get the most out of the Vidjil platform?
  • Clément Chesnin, Studying sets of samples, computing statistics
12:30 – 14:00 Lunch
14:00 – 15:00 Talks: Immunology and Hematology (1)
  • Anne Desmares (CHU Rennes 🇫🇷)
  • João Meidanis (Boldrini Center 🇧🇷)
  • Mindaugas Stoškus (U. Vilnius 🇱🇹)
  • Other talks TBA
15:00 – 16:30 Practical sessions 1
  • Usage of the Vidjil Web platform, analysis of participant and/or public data
  • (both tutorial and advanced usage)
17:00 – 17:30 Talks: Bioinformatics software, regulation and certification
  • Mikaël Salson, Processing VDJ recombinations still faster
  • Mathieu Giraud, Testing and Certifying Analyses of V(D)J Recombinations
20:00 Dinner

Thursday 23 May

9:00 – 10:30 Talks: Immunology and Hematology (2)
  • Cédric Pastoret (CHU Rennes 🇫🇷)
  • Yannick Le Bris (CHU Nantes 🇫🇷)
  • Other talks TBA
11:00 – 12:30 Practical session 2
12:30 – 14:00 Lunch
14:00 – 15:30 Round table
  • Discussion on most wanted features, development priorities
  • Meeting of the Scientific and Technic Commitee
15:30 – 16:00 Conclusion

Registration

The workshop is sponsored by the VidjilNet consortium at Inria. There is no registration fee. To register, please copy, paste and fill the following lines into an email to Clément, Florian, Mathieu and Mikaël :

================================================
First name: 
Last name: 
Function: 
Laboratory/hospital: 
City: 
Country:

I will be present in Rennes:
    [ ] Both days
    [ ] Wednesday 22 May 2024
    [ ] Thursday 23 May 2024

My usage of Vidjil:
    [ ] I use Vidjil at least once a month
    [ ] I use Vidjil occasionnaly
    [ ] I am a new user or I don't use Vidjil
================================================

The two lunches (22 and 23 May) and the dinner of the evening of the 22 May are free for registered participants. For organization purposes, we invite you to register as soon as possible and before 3 May 2024.

Rennes

Dmitry Djcuce (source: Wikimedia Commons)


Practical information in Rennes

The workshop takes place at Université de Rennes on the Beaulieu campus. More details will follow.

Organizers

The workshop is organized by Clément Chesnin, Mathieu Giraud, Mikaël Salson, Florian Thonier, from CRIStAL, Inria Lille and the VidjilNet consortium.