Immune Repertoire Analysis
with Vidjil

Rennes (France), 12-13 October 2026

V(D)J recombinations in lymphocytes are essential for immunological diversity. They are also useful markers of pathologies, and in leukemia, are used to quantify the minimal residual disease during patient follow-up. High-throughput sequencing (NGS/HTS) now enables the deep sequencing of lymphoid populations. With dedicated Rep-Seq bioinformatics methods and software, clinicians and researchers can now qualify and sometimes quantify the heterogeneity of these lymphoid populations.

This seventh workshop is intended for users and developers of Vidjil, to share experience, protocols and results, to raise questions and decide development priorities, and possibly to set up new collaborations between biologists and bioinformaticians. The workshop includes hematology, immunology and bioinformatics talks from an invited speaker and from the users and developers of Vidjil, and practical hands-on sessions on participant data. The registration is free but mandatory, and a remote participation to some of the sessions is possible.
The Vidjil Workshop usually takes place every 18 months. The previous workshops (2016, 2017, 2019, 2020, 2022), 2024) gathered at each edition between 30 and 40 scientists from 5 to 7 countries. The 2026 edition gathers 37 people from Austria, Brazil, Czech Republic, France, India, Iran, Italy, Lithuania, and Switzerland.

▶️ remote Partial hybrid participation: https://visio.numerique.gouv.fr/vid-2026-jil


Program

The workshop includes an invited talk, hematology and bioinformatics talks from the users and developers of Vidjil, and practical hands-on sessions on participant data. We expect that one participant from each group will do a short presentation of his research or clinical work, and, if applicable, of the results obtained with Vidjil or with other software.

For the practical sessions, the participants are invited to bring a laptop and some of their NGS data (fasta / fastq / fastq.gz files). The data can also be uploaded into user accounts on app.vidjil.org before the workshop. We also provide public test data for the people who do not currently have their own NGS Rep-Seq data.

Monday 12 October

9:00 – 9:45 Registration, coffee
9:45 – 10:00 Introduction
10:00 – 12:30 Talks: Bioinformatics, Algorithms, Mathematics ▶️ remote
  • Mathieu Giraud, Mikaël Salson (Vidjil team, Lille, 🇫🇷) Introduction to the Vidjil platform
  • Lou Scotto di Covella (Vidjil team, Rennes, 🇫🇷): MRD spike-ins analysis with Vidjil
  • Sami Amara (Vidjil team, Rennes, 🇫🇷): Processing VDJ recombinations still faster
  • Nika Abdollahi (Teheran, 🇮🇷): Impact of conceptual choices on computational AIRR analysis
  • Angie Soler (Campinas, 🇧🇷): Understanding B-ALL via Maximum Mean Discrepancy
12:30 – 14:00 Lunch break
14:00 – 15:00 Talks: Immunology and Hematology 1 ▶️ remote
  • Rathana Kim (Paris, Robert Debré, 🇫🇷), Clonal marker identification for minimal residual disease in adult B-cell acute lymphoblastic leukemia
  • Mindaugas Stoškus (Vilnius, 🇱🇹), TBA
  • Anne Langlois de Septenville (Paris, Pitié Salpêtrière, 🇫🇷), Use of Vidjil for mutational status determination in CLL and other ongoing projects in hematology
  • Benjamin Podvin (Lille, 🇫🇷), Clinical use of V(D)J markers: From lymphoblast to plasma cell
15:00 – 15:15 (Remote) group picture
Filling out the Vidjil 2026 Survey: usages and most wanted features ▶️ remote
15:15 – 15:30 Coffee Break
15:30 – 17:00 Session Vidjil's Future ▶️ remote

Mikaël Salson & Mathieu Giraud (Vidjil Team, Lille, 🇫🇷): 15 years of open-source Vidjil development

Frédéric Davi (Paris, Pitié Salpêtrière, 🇫🇷): Vidjil, collaborators and competitors

Florian Thonier & Guillaume Noël (Vidjil Team, Rennes, 🇫🇷): Towards Eviclona
  • Startup objectives and roadmap
  • CE-IVD certification
  • Future of the VidjilNet consortium
Mikaël Salson & Mathieu Giraud (Vidjil Team, Lille, 🇫🇷): Continuing research and collaborative development
Preparation of the 2026 exceptional VidjilNet general assembly (for consortium members)
20:00 Dinner: La Taverne de la Marine2 place de Bretagne, 35 000 Rennes

Tuesday 13 October

▶️ remote
9:30 – 11:00 Talks: Immunology and Hematology 2 ▶️ remote
  • Mario Nuvolone (Pavia, 🇮🇹), Protein sequencing to detect and follow (small) B cell /plasma cell clones
  • Yannick Le Bris (Nantes, 🇫🇷), Clonality by capture: from tissue to cell-free DNA
  • Sylvain Carras (Grenoble, 🇫🇷), Assessing the informativeness of cfDNA in peripheral T-cell lymphomas
  • Françoise Solly (Lausanne, 🇨🇭), Utilisation de VIDJIL au laboratoire d’hématologie du CHUV
  • Introduction to the practical session
11:00 – 11:15 Coffee Break
11:00 – 12:30 Practical sessions
  • Usage of the Vidjil Web platform, analysis of participant and/or public data
  • (both tutorial and advanced usage)
  • Last chance to fill out the Vidjil 2026 Survey for most wanted features
12:30 – 13:30 Lunch break
13:30 – 14:00 General discussion and conclusion ▶️ remote
  • Survey results, discussion on most wanted features, development priorities
  • Reflexion hackathon on most wanted features and new tools
  • Meeting of the Scientific and Technic Committee
14:00 – 15:00 Informal discussions (on-site)

Registration

The workshop is sponsored by the VidjilNet consortium at Inria. There is no registration fee but it is mandatory to register. To register, please copy, paste and fill the following lines into an email to Florian, Guillaumme, Lou, Mathieu and Mikaël, before Thursday, October 1st. The registration for the workshop is closed, but it is still possible to register for remote attendance

================================================
First name: 
Last name: 
Function: 
Laboratory/hospital: 
City: 
Country:

I will be present in Rennes:
    [ ] Both days
    [ ] Monday 12 October 2026
    [ ] Tuesday 13 October 2026

[ ] I will attend remotely

My usage of Vidjil:
    [ ] I use Vidjil at least once a month
    [ ] I use Vidjil occasionally
    [ ] I am a new user or I don't use Vidjil
================================================

The two lunches (12 and 13 October) and the dinner of the evening of the 12 October are free for registered participants.

Rennes

Dmitry Djcuce (source: Wikimedia Commons)


Practical information in Rennes

The workshop takes place at Université de Rennes on the Beaulieu campus, in the PNRB building. To go the the PNRB, take the C4 or C6 bus and stop at Les Préales.

Organizers

The workshop is organized by Sami Amara, Mathieu Giraud, Guillaume Noël, Mikaël Salson, Lou Scotto di Covella and Florian Thonier, from CRIStAL, Inria and the VidjilNet consortium.